have an idea—why don’t we try creating a launcher? We could first use C++ to create a Qt application and register QQuickVTKRenderItem with Qt in advance. With this, the launcher would be completed, and then we could expose this launcher to Python-Embedding, allowing the launcher to execute commands from Python. Wouldn’t this also allow PyQt or PySide6 to run a QtQuick interface while achieving compatibility with VTK? My C++ coding skills are very limited, but I think this could be feasible. Perhaps this GitHub project might offer more inspiration: GitHub - skywind3000/PyStand: 🚀 Python Standalone Deploy Environment !!.